Abstract
The purpose of this report is to record briefly the clinical notes and pathologic findings in three uncommon cases of chronic renal disease occurring in comparatively young persons, associated with a marked degree of nitrogen retention and running a rapidly fatal course. In addition, because of the absence of a definite etiologic factor, together with an unusual appearance of the kidneys at necropsy, the importance of a congenital basis is emphasized, as an etiologic factor in these and similar cases. REPORT OF CASES Case 1.1 —J. M., a white man, aged 37, a policeman for the last fifteen years, who was admitted to the Jefferson Hospital in the service of Dr. H. A. Hare, April 12, 1921, complained of shortness of breath. His family history was negative. He had had typhoid fever at 13, gonorrhea at 22 and influenza at 33, from all of which he had apparently made
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