Abstract

We describe the ovaries of a guinea pig in which the experimentally produced hypotypical condition was more advanced than in any of the other animals which we observed. In this case the underfeeding not only affected the activity of the granulosa, but also of the connective tissue. In consequence of a lowered activity of the connective tissue a concrescence of follicles takes place in numerous cases in both ovaries. A lowering of intraovarian pressure in such ovaries leads to a relative preponderance of what corresponds to the interstitial gland in the ovaries of certain other species. The concrescence of ovarian follicles is analogous to the union of neighboring acini in the mammary gland and thyroid. It is a phenomenon which occurs probably in all or the majority of glandular structures.

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