Abstract
The concentration of trace elements in human lithogenic bile.
Highlights
The trace element content of human bile was studied to find the difference between hepatic, common bile duct and gallbladder bile
We found that only 3 molar (3M) HC1 can form a solution with bile; HC1 of molarity less than 3M failed to form a solution and ifmolarity was more than 3M, it coagulated the bile
The high levels of Mg, P, pb, Fe and Mn noticed in this study may be due to secretion of these metals from the gallbladder mucosa either in ionic or compound forms, this may be true in the case of Ni as it is only found in gallbladder bile; some of these elements may play a role in forming the gallstone nidus
Summary
The trace element content of human bile was studied to find the difference between hepatic, common bile duct and gallbladder bile. Twenty-two elements were studied (Table 1) 2 elements were assessed for the first time (Ba & Si); out of 22 elements only 12 can be detected in human bile, the mean values of those elements in hepatic, CBD & gallbladder bile and regardless the source are given (Table 2).
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