Abstract
Monovalent cations decrease the initial rate of uptake of the membrane potential probe 2-(dimethylaminostyryl)-1-ethylpyridinium (DMP) into metabolizing cells, showing that the cells are depolarized. A steep decrease in this rate was found even at low cation concentations, reaching 62%, 42%, 58% 40% and 40% at high concentrations of K +, Rb +, Cs +, Na + and Li +, respectively. The corresponding concentrations at which half-maximum decrease was found were 0.22, 0.36, 1.2, 17 and 17 mM. These values are of the same order of magnitude as the half-saturation concentrations for monovalent cation uptake by the yeast.
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Schedule a callMore From: Biochimica et Biophysica Acta (BBA) - Biomembranes
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