Abstract
The aim of the study was to investigate the microbiota in the cervical part of the teeth in the gingival margin of the oral cavity of rats at the end of the second, fourth and sixth weeks of the experimental action of the opioid analgesic nalbuphine. Under the action of opioids for six weeks, changes in the microbiocenosis in the studied subbiotope of the oral cavity of animals were found, which manifested themselves in the early stages by the appearance of gram-negative anaerobes, gradual increase in opportunistic pathogens, formation of dental biofilm experiment.
Highlights
13 October 2020THE COMPOSITION OF THE MICROBIOTES OF THE NECK PART OF THE TEETH IN THE AREA OF THE GUM EDGE OF RATS AT THE END OF THE SECOND, FOURTH AND SIXTH WEEKS OF OPIOID INFLUENCE
The aim of the study was to investigate the state of the microbiome in the cervical part of the teeth in the area of the gingival margin of the oral cavity at the end of the second, fourth and sixth weeks of the experimental action of the opioid analgesic nalbuphine
In the study of the microbiome in the cervical part of the teeth in the gingival margin of rats after two weeks of action of the opioid analgesic nalbuphine, we found changes in the species and quantitative composition of bacterial groups
Summary
THE COMPOSITION OF THE MICROBIOTES OF THE NECK PART OF THE TEETH IN THE AREA OF THE GUM EDGE OF RATS AT THE END OF THE SECOND, FOURTH AND SIXTH WEEKS OF OPIOID INFLUENCE. KEYWORDS opioid, microbiological studies, rats, oral microflora
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