Abstract
The development of new means for topical therapy and prevention of scar formation of moisturizing and protective action based on ectoin can be promising. The optimal form is hydrogels, because of their adhesive and plastic properties, easily distribution and remaining for a long time on the skin. The purpose of this study was the development of the composition and technological research of the gel with ectoin for the prevention of skin scars. To select the optimal gel-forming agents’ technological studies (external characteristics, drying characteristics and film quality on the skin and on model surfaces, skin moisture, pH, the active substance release, thermal and colloidal stability, rheological properties) of model samples based on gel-forming agents, used in protective and anti-scar creams carried out. The composition of polymers xanthan and sodium carboxymethyl cellulose selected, which has improved adhesion and moisturizing properties, to reduce the frequency of application and provide a prolonged effect. The optimal concentration of dimethicone to enhance the protective effect and enhance the hydrophobic effect selected. The technological characteristics of model samples of ectoin gel investigated: description, pH, thermal and colloidal stability, viscosity, microbiological purity. The results indicate that the gel has the necessary technological characteristics that determine its quality. Thus, as a result of technological research, the composition of the anti-scar ectoin gel was developed.
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