Abstract
In Reply. —The data of Verebey et al are useful in interpreting the plasma concentrations of the MDMA measured in the patient we reported. The dose reported by the patient was certainly underestimated. The ratios of MDA/ MDMA concentrations were never more than 0.02. This also suggests an overdose when compared with the ratios in the data of Verebey et al. The major concern in our letter was to reinforce the warning of Dowling et al 1 that severe consequences have resulted from the use of MDMA. This concern is heightened by (1) a recent report stating that 39% of students at one college campus had tried MDA 2 and (2) the neurotoxic effect of the metabolite MDA cited by Verebey et al.
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