The comparison of post OPCABG complications between opium addicted and non- addicted patients

Abstract

Objectives: Opium addiction is one of the fundamental public health problems today that could influence cardiovascular disease outcomes. Recent studies have shown that opium addiction may increase the risk of postoperative complications in patients undergoing on-pump coronary artery bypass graft surgery. In this retrospective cross-sectional study, we aimed to assess whether opium addiction may affect the postoperative complications of off-pump coronary artery bypass graft surgery (OPCAB) (1).
 Methods: In this cross-sectional study, we searched the clinical records of all patients who underwent OPCAB surgery from 2017/03/21/ to 2018/03/19/ at Afshar and Seyed Al-Shohada Hospitals in Yazd, Iran. We evaluated the patients for postoperative complications. Complete patient demographic and clinical data collected through a review of patient records. Finally, the collected data were analyzed using SPSS software version 18.
 Results: A total of 889 patients (667 (76.2%) non-addicted, 127 (14.3%) opium addicts, and 86 (9.6%) smokers and opium addicts) met our criteria and were included in the study. The average age of the participants was 62.09 ± 9.8 years. Frequency distribution of the most postoperative variables such as intubation duration, intensive care unit (ICU) stay, postoperative bleeding volume, pack cell count, need for fresh frozen plasma (FFP), platelet injection volume, need for reoperation, need for intra-aortic balloon pump, as well as Atrial fibrillation (AF) rhythm showed no significant difference between the three groups. However, the only significant difference between the three groups reported the need for postoperative use of inotropic drugs (p=.001).
 Conclusions: According to the results, the only complication that differed significantly in the three patient groups after OPCAB was the need for inotropic drugs.