The Comparison of Clinical Characteristics of Acute Decompensated Heart Failure Patients between JCARE-CARD Japan and dr. Kariadi Hospital Registry

Abstract

Background: _Heart failure (HF) is a major public health problem due to the high prevalence, poor prognosis, and huge costs contributed by frequent hospital admissions and prolonged care. Clinical characteristics of patients with HF might differ among different regions and races and low socioeconomic status was associated with increased incidence of heart failure. Indonesia dan Japan are both Asian countries with different race and socioeconomic status. No previous study has examined the difference of clinical characteristics between Indonesia dan Japanese HF patients.Objective: To investigate HF patients demographic and clinical characteristics in Indonesia and compare with Japanese registryMethods: In this retrospective observational study, patients presenting with acute decompensated heart failure (ADHF) at dr. Kariadi Hospital (RSDK) were consecutively recruited during 2014-2015 hospitalization period. Baseline data including demographic, clinical characteristics, laboratory data on admission, medication use before hospitalization, and length of stay during hospitalization were collected from medical record using the form of the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). The descriptive analysis was performed to compare those HF characteristics.Results: A total of 246 ADHF patients in RSDK registry were included with average age of responden was 56.4 years-old and 57.3% were male. Etiology was predominantly ischemic heart disease (IHD) in 60.6%, average left ventricular ejection fraction 40.1% and length of hospital stay was 8.8 days. Compared to Japanese registry, the characteristics of clinical status and laboratory data on admission were almost similar between studies except for higher prevalence of ischemic heart disease, renal dysfunction and dyslipidemia but lower prior stroke in RSDK study. The average length of stay at hospital was longer in Japanese registry (8.8 days vs. 33.9 days).Conclusion: Ischaemic heart disease and renal dysfunction more prevalent in RSDK registry, but prior stroke and length of stay at hospital higher in Japanese registry of hospitalized ADHF patients.