The Comparison of Clinical and Biochemical Outcomes in Off-Pump and Conventional Coronary Artery Bypass Grafting Surgery

Abstract

Objective: There is no common concencus the clinical results of coronary artery bypass grafting (CABG) surgery patients who underwent off-pump or conventional techniques. Our aim of this study was to compare the changes of myocardial functions, patients’ clinical results, biochemical marker release during surgery and postoperatively in On- and Off-Pump CABG surgery. Method: A consecutive series of 50 coronary artery disease (CAD) patients who underwent elective CABG surgery included for this study. The patients were divided into two groups (Group 1, N = 25 and group 2, N = 25). Demographic data including the patients’ age, gender, body mass index (BMI), diseased coronary artery numbers, LVEF were similar. Postoperative red package blood cell, fresh frozen plasma, and thrombocyte requirements were high in On-Pump group (p p p > 0.05). However, cTnI levels were significantly higher in the on-pump group (p = 0.0001). Postoperative LVEF decreased significantly in both groups when compared to preoperative echocardiography examinations (p = 0.001). But the changes of postoperative LVEFs in both groups were not statistical significant (p > 0.05). Conclusion: Our study results indicated that cardiac enzyme release was high after On-Pump CABG surgery. However, LVEF decreased in both techniques. There were some advantages of OPCAB operations such as decrease of inflammatory responses and angina pectoris incidence due to extracorporeal circulation; however, these techniques did not affect postoperative mortality and morbidity. Therefore, in selected cases to provide longer operation time, Off-Pump CABG could be used but it has no superiority over On-Pump CABG surgery.