THE COMPARISON OF ANTIFUNGAL EFFECT BETWEEN GARLIC EXTRACTS AND ALKALINE PEROXIDE TOWARDS CANDIDA

Abstract

Background: Candida albicans is a microorganism found on denture plaque. Candida albicans can penetration and accumulated on surface of the denture and then to infection the soft tissue that causes denture stomatitis. Denture cleanser has effectivity of anti-fungal is alkaline peroxide. Naturally denture cleanser contain of anti-fungal is garlic. Purpose: This research is to analyze inhibition effectivity of garlic extract concentration 2,5%, 5%, 10%, 12,5%, 15%, and alkaline peroxide to Candida albicans growth on acrylic heat cured. Method: This research uses true experimental with post test only with control group design. Garlic extract concentration 2.5%, 5%, 10%, 12.5%, 15%, and alkaline peroxide. The method of this research uses diffusion method with the measure of inhibition zone. Result: The result of the research garlic extract concentration 2.5%, 5%, 10%, 12.5%, 15%, and alkaline peroxide to Candida albicans growth have inhibition zone are 11.29mm, 13.25mm, 16.30mm, 18.2mm, 19.46mm, and 15.33mm. The result of normality test with Saphiro-Wilk is p>0,05, Levene’s test that results is p=0,575 (p>0,05) so the all data are normality and homogenity. Analyze data uses One Way ANOVA that result is p=0,000 (p<0,05) are differences inhibition effectivity and next testing of Post Hoc Bonferroni show that significant differences between each group. Conclusion: The research is the differences inhibit effectivity of the garlic extract concentration 2,5%, 5%, 10%, 12,5%, 15%, and alkaline peroxide to Candida albicans growth on acrylic heat cured. Garlic extract in 10%, 12.5% and 15% have a bigger effectivity of inhibition than alkaline peroxide to Candida albicans growth.