The Comparison of 25-Hydroxyvitamin D3 between Patients With and Without Cervical Cancer

Abstract

BACKGROUND: Vitamin D was currently believed to have effects on numerous cancer pathogenic processes. AIM: This study was to assess the correlation of Vitamin D serum level in women with carcinoma cervix and also evaluate the effect of carcinoma cervix on the Vitamin D serum. METHODS: This was an observational with a cross-sectional study. Participants were women with cervical cancer who have not received any treatment, presented to the Oncology Clinic of the Obstetrics and Gynecology Department of Dr. Hasan Sadikin General Hospital, and women without cervical cancer. The level of Vitamin D3 was analyzed in the Serology Laboratory of Clinical Pathology Department of Dr. Hasan Sadikin General Hospital. RESULTS: There were 113 participants consisted of 58 women with cervical cancer and 55 healthy women. Mean levels of Vitamin D3 were significantly lower in cervical cancer group than non-cervical cancer group (26.74 ± 13.166 vs. 32.16±14.86, p = 0.022). CONCLUSION: The level of Vitamin D3 was found to be significantly higher in the non-cervical cancer group than cervical cancer group.