The comparison analysis of low-dose dobutamine electrocardiography stress test and echocardiography stress test in the diagnosis of coronary artery disease

Abstract

Objective To compare low-dose dobutamine electrocardiography (ECG) stress test and echocardiography (ECHO) stress test in the diagnosis of coronary artery disease (CHD).Methods Fifty-six patients with CHD were chosen.They were given dobutamine before test in the speed of 1 μ g/(kg· min ),and gradually increased to 5 μ g/(kg·min).Low-dose dobutamine ECG stress test,ECHO stress test and coronary angiography (CAG) were performed,and the results were compared.The sensitivity,specificity and accuracy of low-dose dobutamine ECG stress test and ECHO stress test were calculated.Results CAG showed 37 cases of patients with coronary artery stenosis.The sensitivity,specificity and accuracy of low-dose dobutamine ECG stress test were 62.16％ (23/37),73.68％ (14/19) and 66.07％ (37/56).The sensitivity,specificity and accuracy of ECHO stress test were 86.49％ (32/37),52.63％ (10/19) and 75.00％ (42/56).There were significant differences in sensitivity and specificity between two test methods (P ＜0.05).Conclusions In the diagnosis of CHD, low-dose dobutamine ECG stress test has high specificity,and ECHO stress test has high sensitivity and accuracy.Combination of them has high clinical value. Key words: Dobutamine; Electrocardiography; Echocardiography; Coronary disease