Abstract

The combined antibacterial activity of Face cleansing agents and Psidium guajava leaf Extract on Methicillin- resistant Staphylococcus aureus (MRSA) was evaluated. The plant material was extracted and the phytochemical analysis done using standard procedures. The extract and face cleansing agents were tested for antibacterial activity using agar well diffusion technique. Phytochemical studies revealed that Psidium guajava contains Glycosides, Saponins, Tannins, Resin and Terpenoids as its constituents. The result of the antibacterial assay showed that all the face cleansing agents were ineffective against the MRSA isolates, however, two of the face cleansing agents were slightly effective against normal laboratory strains of Staphylococcus aureus Furthermore, after incorporating the P. guajava extract into the face cleansing agents, it produced a synergistic antibacterial activity against the MSRA isolates. Thus, the study has shown that P. guajava possesses potent antibacterial activity and could be employed in the eradication of infections caused by MSRA isolates.

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