The combination of papillary thyroid microcarcinoma and diffuse toxic goiter in a patient with acromegaly

Abstract

Acromegaly is a severe multifactorial neuroendocrine disease accompanied by increased secretion of growth hormone, which contributes to the active proliferation of cells of various tissues in the body. Among the complications of the disease, cardiovascular pathology predominates, and is often the cause of increased mortality. Recently, however, with acromegaly, cases of detection of thyroid cancer are increasingly described. The causes and increasing prevalence of benign and malignant neoplasms of the thyroid gland in patients with acromegaly cause much debate in the medical world. The American Thyroid Association guidelines do not include acromegaly in the list of conditions with an increased risk of thyroid cancer but a number of experimental and epidemiological data indicate a high likelihood of such complications. We present a clinical case of diagnosed papillary thyroid cancer in a patient with acromegaly.