Abstract
Abstract Methods by which morphine may be determined colorimetrically are discussed and the present official method criticised. The reaction described by Pride and Stern, which depends upon the oxidation of morphine with iodic acid followed by treatment with ammonium bicarbonate and nickel chloride to give a green colour has been found satisfactory. Improved extraction procedures for the separation of morphine from extraneous material in a number of galenical preparations are suggested and application of the colorimetric reaction to morphine residues so obtained, is described.
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