Abstract
Objective To explore the characteristics of the cognitive changes in patients with lacunar infarction(LI) after carotid artery stenting(CAS). Methods Neuropsychological tests were conducted in 43 patients with LI and carotid stenosis before and 1 month, 6 months, 12 months after CAS and the scores were compared with those of 41 healthy cases. Results Compared with control group, MMSE scores (26.33±1.94), memory and executive function in therapy group lowered obviously. There was statistical difference (P<0.05 or P<0.01). Compared with before CAS, MMSE scores of 1 month (27.17±2.15), 6 months (27.17±2.15), 12 months (28.15±1.98) after CAS, memory and executive function in therapy group were all better obviously.There was statistical difference (P<0.05 or P<0.01). Conclusion In acute stage of patients with LI (with in 1 week), most cognitive impairment was severe. Most cognition disorders was improved to normal level 12 months after CAS.The mechanism may be associated with the improvement of chronic cerebral insufficiency. Key words: Lacunar infarction; Carotid stenosis; Antery-intervention therapy; Cognition disorders
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