Abstract
The authors report the case of a 42-year-old man with a rare coexistence of clear cell renal cell carcinoma and gastrointestinal stromal tumor of the stomach with concurrent portal vein metastasis. After surgical resection of the two original masses, the patient was treated with sunitinib malate to control the portal vein metastasis. The metastatic lesion completely disappeared after two cycles of treatment. This is the first known reported case of synchronous clear cell renal cell carcinoma and gastrointestinal stromal tumor with distal metastasis, and the first report of the favorable efficacy and safety of sunitinib in treating this rare synchronous dual malignancy.
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