THE CO-EXISTENCE OF HYPERTHYROIDISM AND PREPUBERAL EUNUCHOIDISM IN A MALE

Abstract

THE problem of the interrelationships between the thyroid gland and the gonads has been the subject of considerable study and controversy. Most of the reports concern themselves with the effect of thyroid activity on the gonads and only a rare reference has been made to the opposite relationship. These changes in gonadal function in the female have been reported frequently because menstrual disturbances lend themselves easily to clinical observation. Presumptive gonadal changes in the male have received much less attention and few reports have been published. Not all observers believe that a direct relationship exists between these two endocrine organs. Van Dyke (13) concluded that thyroid activity probably has no significance in the regulation of gonadal function. Moore (9) stated that experimental data had not yet established the existence of any direct relationship between the thyroid and the testes although there was good evidence of the occurrence of indirect functional associations mediated probably...