Abstract

Objective: To explore the clinicpathologic features and MRI manifestations of the thoracic lumbar tuberculosis by underwenting MRI and pathological examinations. Methods: 34 cases of Thoracic lumbar tuberculosis were collected which underwent MRI examination and confirmed by pathology or treatment of anti-TB drugs, the clinical cure from June 2008 to June 2012 in our hospital. The first MRI was performed on all patients, to determine the MRI findings, and surgical treatment for pathological examination in order to determine the pathological features. Results: 34 patients with 81 vertebral involvement, in which two adjacent vertebral involvement is the common, accounting for 72.25%, vertebral showed uneven long T1, long T2 signal. Intervertebral disc abnormalities accounted for 90.17%, the performance showed long T1, long T2 signal changes in the intervertebral disc damage, often accompanied by disc space narrowing or disappear. Paraspinal abscess accounted for 90.67%, often more than vertebra, up and down across one or more vertebral bodies showed long T1, long T2 signal. The vertebrae were damaged kyphosis or (and) the posterior longitudinal ligament abscess caused by the dural sac and spinal column with pressure accounted for 74.72%. In enhanced scan, vertebrae, intervertebral discs showed heterogeneous enhancement, paraspinal abscess was curved or ring enhancement. The pathological diagnosis may be obvious to confirm the degree of swelling and lesions. Conclusion: By doing the MRI and pathologic examinations, it can determine the clinical and pathological features and MRI findings of spinal tuberculosis patients with Thoracic lumbar spinal tuberculosis, and lay a reliable foundation for the treatment of the subsequent treatment.

Highlights

  • Spinal tuberculosis is the most common extrapulmonary tuberculosis, which accounts about 65% in Osteoarticular tuberculosis

  • Thoracic lumbar tuberculosis takes the percentage of 91% [1]

  • World Health Organization of global tuberculosis report show that in recent years, tuberculosis infection recovered in the globe [4], with the growth of autoimmune diseases and the increase in drug-resistant bacteria, Tuberculosis bacteria like to grow in blood-rich places; and spine vertebral maybe one of the ideal places for mycobacterium tuberculosis to stay

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Summary

INTRODUCTION

Spinal tuberculosis is the most common extrapulmonary tuberculosis, which accounts about 65% in Osteoarticular tuberculosis. Due to its concealed onste and slow developments with the reason that traditional x-ray and CT do not show early vertebral inflammation and inflammatory changes with spinal meninges and discitis, the clinical misdiagnose rate in relatively high [2,3]. In the past few years, MRI (Magnetic resonance imaging) offered onenew detective method in Thoracic lumbar tuberculosis. To highlight the recognition of the disease, the study tried to identify the clinic pathologic features and the manifestations of MRI by retrospective analysis of 34 cases patients of thoracic lumbar tuberculosis, of which the final diagnosis are all in our hospital. This study follows the procedures and the ethical standards which established by the Hospital Ethics Committee

General Information
Research Methods
MRI Check Results
Pathological Diagnosis
DISCUSSION
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