Abstract

Allogeneic hematopoietic and bone marrow cell transplantation causes acute and chronic graft-versus-host disease (GVHD), which is considered a severe side effect. The liver, gut, and skin are well-known primary target sites of acute and chronic GVHD. However, whether the kidney is affected by GVHD remains uncertain. In the present study, we examined the clinical and pathological characteristics of the kidney in acute GVHD in Dark Agouti-to-Lewis rat bone marrow transplantation.

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