The clinical value of transrectal ultrasound elastography and the contrast-enhanced ultrasonography in early diagnosis of prostate cancer

Abstract

Objective To evaluate the clinical value of transrectal real-time elastography(TRTE) and contrast-enhanced transrectal ultrasound(CETRUS) in early diagnosis of prostate cancer. Methods From August 2016 to August 2017, 119 patients with suspected prostate cancer were divided into low risk group (n=21) , moderate risk group (n=24) and high risk group (n=28) according to Gleason sores. The rest 46 patients were found with benign prostatic hyperplasia (BPH group) enrolled in this study. The transrectal ultrasound(TRUS), TRTE and CETRUS were performed for all patients. The accuracy rate of prostate cancer detection using TRUS, TRTE and CETRUS were compared with the pathologic results. Results There was no statistical differences of accuracy rate between low risk group and BPH group with TRTE and CETRUS. There were statistical differences of accuracy rate between low risk group and BPH group with the combination TRTE and CETRUS. Totally 119 patients underwent TRUS, TRUS with TRTE、TRUS with CETRUS and TRTE with CETRUS. The sensitivity, specificity, positive predictive value, negative predictive value of TRUS, TRTE, CETRUS, TRTE and CETRUS in diagnosis of prostate cancer was 46.77%, 58.18% , 49.23%, 55.77%, 66.13%, 70.91%, 65.00%, 71.93%, 80.64% , 81.82% , 78.95%, 83.33%, 90.32%, 85.45%, 88.68%, 87.50%, respectively. Conclusions CETRUS combined With TRTE can detect early prostate cancer and contribute to differential diagnosis between benign and malignant lesions. Key words: Prostatic Neoplasms; Ultrasonography; Elasticity Imaging Techniques; Angiography; Rectum