Abstract
A prospective clinical evaluation of plasma and urine carcinoembryonic antigen (CEA) in haematuria and urothelial carcinoma is presented. This study, in 325 patients, has shown that plasma CEA is of no value in the differential diagnosis of haematuria, T1 tumours or in the assessment of advanced bladder tumours with metastatic disease. Urinary CEA can be raised in the presence of urothelial carcinoma but is not a reliable diagnostic or prognostic index.
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