The clinical value of new rapid pathological diagnostic technology in nasopharyngeal biopsy under nasal endoscopy

Abstract

Objective To explore the clinical value of new rapid pathological diagnostic technology in nasopharyngeal biopsy under nasal endoscopy. Methods Twenty-one nasopharyngeal carcinoma patients who were confirmed by nasopharyngeal biopsy and routine pathological diagnosis were selected, they underwent a new rapid pathological diagnostic technique for real-time cytology in the endoscopic biopsy process; the doctors adjusted the biopsy operation plan according to the rapid pathological diagnostic results. The clinical value of new rapid pathological diagnostic technique in nasal endoscopic nasopharyngeal biopsy was analyzed. Results The new rapid pathological diagnostic technology required little space and had no pollution. The diagnosis took about 2 to 3 minutes and did not affect the normal puncture biopsy operation. In 21 patients with nasal endoscopic nasopharyngeal biopsy, few tumor cells were found in 3 cases (14.3%), tumor cells were not found in 2 cases (9.5%), so the operation was repeated at the same time till the re-biopsy met the requirements. Conclusions Nasal endoscopic nasopharyngeal biopsy is an important method to diagnose nasopharyngeal carcinoma confirmedly. The new rapid pathological diagnostic technology can provide real-time pathological diagnosis during nasal endoscopic nasopharyngeal biopsy and improve the quality of puncture tissue, by that way it can ensure the first success rate of nasal endoscopic nasopharyngeal biopsy. Furthermore, the cost of this technology is low and it is suitable for implementation in hospitals at all levels. Key words: New rapid pathological diagnostic technique; Nasopharyngeal carcinoma; Nasopharyngeal biopsy under nasal endoscopy; Positive rate; Clinical value