The clinical value of capsule endoscopy for diagnosis and treatment of Crohn's disease

Abstract

Objective To evaluate the value of capsule endoscopy(CE)in diagnosis, management and prognosis of crohn's disease(CD). Methods Four diagnosed CD patients and 22 patients with suspected CD underwent CE. The lesion location and drug therapy were analysed prospectively. Follow-up of one year was conducted to evaluate the disease and the effectiveness of therapy. Results There was an increase in detection rate of small bowel involvement, namely, from 57.7% to 80.8%, and a decrease in symptomatic treatment and an increase in medication of hormone and immune inhibitors. After the follow-up of 12 months, 12 suspected CD patients were confirmed, and 2 patients were excluded. Variance analysis of CRP, CDAI, IBDQ and LS were conducted by repeated measures (P<0.05)and that meant the therapy was effective. Conclusion CE is useful for diagnosis, treatment and prognosis of CD. Key words: Intestine, small; Crohn's disease; Capsule endoscopy; Diagnosis; Therapeutic uses