Abstract
With the invention of the differential pupilloscope by Hess<sup>1</sup>and the careful studies by him and his pupil Groethuysen,<sup>2</sup>a new basis was created for the study of the pupillary reactions and for the exact localization of lesions in the reflex arc. The use of this instrument and its value in the study of neurologic cases has been well presented in this country in the papers of O. Barkan<sup>3</sup>and Adler.<sup>4</sup>These authors pointed out that the Argyll Robertson pupil may be detected by means of this instrument at a stage when an ordinary examination of the pupil gives no definite findings, and that in many cases the location of lesions or the detection of multiple lesions in the reflex arc is possible only by the use of the pupilloscope. The progress of such lesions during treatment may also be accurately checked by this
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