The clinical study of using a modified type of povidone- iodine for bowel preparation to prevent infection after prostate biopsy

Abstract

Objective To observe the effect of prevention of infection using a modified type of povidone-iodine for bowel preparation after transrectal ultrasound-guided prostate biopsy. Methods Collecting 318 casesdiagnosed of suspected prostate cancer were divided into two groups by random digital table method. The control group underwent routine bowel preparation, with the concentration of 1% povidone iodine 300 ml in half an hour before the puncture and keeping 5-10 minutes; the experimental group underwent modified povidone iodine bowel preparation, with the concentration of 3% povidone-iodine 50 ml in 10 minutes before the punctureand keeping 10 minutes. All patients were used sensitive antibiotics in 2 hours after prostate biopsy to prevent infection, then compared the two group's infection rates. Results The incidence of infection in the experimental group was 1.25% (2/160), which was significantly lower than 7.59% (12/158) in the control group, the difference was statistically significant (χ2=7.604,P <0.01). Conclusions The modified povidone iodine intestinal preparation can prevent postoperative infection of transrectal ultrasound-guided prostate biopsy effectively and can be used in clinical. Key words: Enema; Prostate; Biopsy, needle; Infection