The clinical significance of test on microalbuminuria in patients with arterial hypertension.

Abstract

The study was carried out to analyze rate of occurrence of microalbuminuria among patients with essential arterial hypertension and to evaluate its clinical and prognostic significance. The examination sampling included 250 patients. The anamnesis data collection, detection of body mass index, measurement of arterial pressure were implemented. The screening test of microalbuminuria detection in morning one-time portion of urine was applied using test-stripe "MicroAlbufan". The level of creatinine in blood was detected and velocity of glomerular filtration was calculated. The statistical processing of data was implemented using both applied statistical program STATISTICA v.6 and techniques of descriptive statistics. The difference considered reliable at p<0.05. The microalbuminuria was diagnosed in most of the patients with arterial hypertension. The arterial ypertension increases with higher velocity of glomerular filtration and decreases with lower velocity of glomerular filtration. Especially neatly this relationship is traced at stage I and II of chronic kidneys disease. It was found that content of microalbuminuria increases with increasing of degree of arterial hypertension. Moreover, the values of arterial hypertension is impacted by tobacco smoking, intake of anti-hypertension medications and pharmaceuticals with nephro-protecting characteristics. The chronic kidneys' disease stage II was diagnosed in 42% of patients with microalbuminuria. This layout permits to widespread possibilities of early detection of chronic kidneys' disease, verification of nosologic nephrological diagnosis and observation of patients by nephrologist and other clinical specialists. Moreover, possibility occurs of timely starting of nephro-protection strategy.