Abstract

Objective To explore the clinical significance of serum procalcitonin ( PCT ) and C-reactive protein( CRP ) in the diagnosis of infection disease.Methods Serum PCT and CRP results were analyzed in 200 patients with infection disease and 80 patients with no-infection disease.Results Serum PCT of 120 patients with bacterium infection before and after treatment were( 23.3 ± 7.8 ) μ g/Land ( 2.1 ± 0.7 ) μ g/L,respectively; and serum CRP were ( 26.7 ± 17.1 ) mg/L and ( 4.9 ± 0.9 )mg/L; serum PCT and CRP of the patients with bacterium infection after treatment significantly differed from that before treatment ( P < 0.01 ).Serum PCT and CRP of patients with bacterium infection was significantly higher than that of patients with virus infection or no infection ( P < 0.01 ).Conclusions During infection,the combination test of PCT and CRP play an important role on the differentiation and diagnosis of diseases.Dynamically testing them has some certain clinical significance and value in the assessment of curative efficacy. Key words: Infection disease; Procalcitonin; C-reactive protein; clinical significance

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