The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction

Abstract

<i>Background</i>: Si-Miao Yong-An Decoction is composed of four herbs: honeysuckle, Radix Sophora, Angelica and Licorice. It has the functions of clearing away heat and detoxification, promoting blood circulation and clearing collaterals. It is a famous ancient formula for the treatment of gangrene, and is now widely used in the treatment of multiple diseases in various systems. <i>Objective</i>: To explore the anticancer action of Si-Miao Yong-An decoction in the clinical application of the treatment of some kinds of malignant tumors. <i>Methods</i>: This paper reviews the sections in classical TCM books and recent report of clinical study of Si-Miao Yong-An Decoction in the treatment of cervical cancer, breast cancer, nasopharyngeal cancer, oral cancer, gastric cancer and etc. <i>Results</i>: The composition of the prescription was first recorded in Shen Yi Mi Zhuan in Han dynasty, and also recorded in the book of Shi Shi Mi Lv and Yan Fang Xin Bian, and it was formally named in Journal of TCM in the year of 1958. It was useful in relieving the clinical symptoms and elevating the life quality besides preventing the recurrence and metastasis of cancer. <i>Conclusion</i>: Si-Miao Yong-An Decoction is effective in treating various malignant tumors and the related complications of the syndrome of blood stasis and heat-toxin. It is promising to provide a new direction for better exploration of traditional Chinese medicine and its application in the treatment of malignant tumors in the future.