The clinical outcomes of idiopathic optic neuritis with no light perception in 21 eyes

Abstract

To evaluate the treatment outcomes of idiopathic optic neuritis with no light perception in 21 eyes. This is a retrospective study. The hospital data of 17 patients (21 eyes) with idiopathic optic neuritis whose visual acuity were no light perception from August 2003 to April 2011 were retrospectively analyzed. These patients were treated with steroid pulse and other drugs. The clinical features, the time of appearance light perception, the best corrected visual acuity and VEP were measured. The follow-up was at least three months. Before the treatment, the average time of occurring no light perception were 1.0 ∼ 90.0 days, except 1 eye was 90.0 days while the other 20 eyes was (12.5 ± 10.6) days. After the treatment, vision improved in 14 eyes (66.7%) from Hand Move/30 cm to 20/20, the average time of appearance light perception was (9.9 ± 7.9) days. The best corrected vision acuity were 1 eye Hand Move, 2 eyes Finger Count, 1 eye 20/2000, 3 eyes 20/1000, 2 eyes 20/800, 1 eye 20/500, 1 eye 20/320, 1 eye 20/125, 1 eye 20/32, 1 eye 20/20. 5 eyes with no VEP wave pattern emerge P(100) after therapy, the other 2 eyes which had P(100) was flatten after therapy. The follow-up found that except 1 eye vision improve outside, the rest eye vision remained stable. The patients with optic neuritis who initially were no light perception should be treated promptly. The prognostic of vision can not be evaluated only by the duration time of no light perception, the appearing-time of light perception and the pattern of VEP.