Abstract
目的 探讨非穿透性小梁手术(nonperforating trabecular surgery.NPTS)联合交联透明质酸钠生物胶(SK胶)或羊膜植入术治疗开角型青光眼的临床疗效及安全性,并对两种不同植入物的临床疗效进行比较.方法 58例(84眼)开角型青光眼患者分为两组.一组行NPTS联合SK胶植入术(36例,53眼),另一组行NPTS联合羊膜植入术(22例,31眼).术后观察两组患者的视力、眼压、滤过泡、并发症,并进行统计学分析比较.结果 术后随访时间6～29个月,平均为(16.2±6.1)个月.SK胶植入组和羊膜植入组术前、术后末次复查时视力差异无显著性(P＞0.05),同时两组间术前、术后视力差异无显著性(P＞0.05).术前、术后6～18个月.两组间眼压差异无显著性(P＞0.05),但术后第24个月时SK胶植入组平均眼压显著低于羊膜植入组(P＜0.05＝.SK胶植入组和羊膜植入组手术质量成功率分别为92.5%和90.3%(P＞0.05).手术完全成功率分别为75.5%和51.6%(P＜0.05).SK胶植入术组和羊膜植入术组术后前房丁达尔征的发生率分别为28.3%和29%,前房积血发生率分别为15.1%和16.1%,低眼压性黄斑痛变发生率分别为15.1%和12.9%,差异无显著性(P＞0.05).结论 NFTS联合SK胶或羊膜两种不同植入物均可有效地降低开角型青光眼的眼压,术后并发症少,并且可有效地保护患者的视功能,是治疗开角型青光眼的有效手术方法.NPTS联合SK胶植入术的手术成功率高于羊膜。
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