Abstract

Objective To investigate the efficiency and safety of wearing orthokeratology by the low and moderate myopia adolescents of different ages. Methods A prospective study. Selected 240 cases with myopia visited ophthalmology outpatient in hospital from February 2014 to December 2014. According to the age, the group was divided into two groups: 7-12 years old group and 13-18 years old group. Each age group was further divided into two groups according to the refractive degree, the low myopia group (-1.00D ~ -3.00D) and the moderate myopia group (-3.25D ~ -6.00D). In the same age groups and same diopter groups, each group was divided into experimental group and control group. The experimental group was wearing the same brand orthokeratology, and the control group was wearing the same brand glasses. The changes of corneal epithelium, corneal endothelial cell density, tear break up time (TBUT) and Schirmer test (Schirmer) were observed in experimental groups before and after 1 year wearing orthokeratology. The changes of visual acuity, diopter, and corneal curvature in the experimental groups wearing orthokeratology were observed before and after 1 day, 1 week, 1 month, 3 months, 6 months and 1 year. The changes of diopter and eye axis length before and after 1 year wearing orthokeratology and glasses in experiment groups and control groups were observed. Results The experiment groups (1) the cornea: there were not found cloudiness, ulcer, perforation and white spots and other serious complications due to corneal infection; (2) the naked eye eyesight: it was all increased after wearing orthokeratology (P 0.05); (6) TBUT: the changes of TBUT before and after wearing orthokeratology had no statistical significance (P>0.05); (7) Schirmer: the changes of schirmer before and after wearing orthokeratology had no statistical significance (P>0.05); The change of diopter and the axial length in experimental group and control group (1) the change of diopter: the change of diopter in experimental group and control group had statistical significant (P<0.05); (2) the change of the axial length: the change of the axial length in experimental group and control group had statistical significant (P<0.05). Conclusions Juvenile myopia patients wearing orthokeratology lens of high permeability materials for oxygen can effectively delay the progression of myopia and control axial growth through scientific fitting. Different ages of low and moderate myopia patients have the same efficacy and safety. Key words: Orthokeratology; Age; Diopter; Tear film; Axial length

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