Abstract

The Clinical Implication of Secondary Pulmonary Bacterial Infection for the Outcome of Critically Ill Patients with COVID-19

Highlights

  • Since December 2019, an unexpectedly emerging novel coronavirus that was denominated as SARS-CoV2, has resulted in a pandemic of respiratory morbidity which was designated as Covid-19

  • Since Covid-19 is an infectious disease that gravely endanger the lives of critically ill patients, thereby it is extremely vital to determine the clinical implication of secondary pulmonary bacterial infection in critically ill ones with severe Covid-19, for the sake of prognostic assessment and therapeutic guidance

  • neutrophil to lymphocyte ratio (NLR), Creactive protein (CRP), neutrophil, lymphocyte, leucocyte and PCT could be used to anticipate the fatality of critically ill patients with Covid-19

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Summary

Introduction

Since December 2019, an unexpectedly emerging novel coronavirus that was denominated as SARS-CoV2, has resulted in a pandemic of respiratory morbidity which was designated as Covid-19. The emerging and evolving Covid-19 has aroused global concern. It leads to a series of clinical manifestations from mild respiratory tract infection to severe pneumonia, multiple organ failure, and death. For critically ill patients with Covid-19, an admission into intensive care units (ICUs) is frequently indicated.[1,2,3,4,5] It has been reported that Covid-19 patients complicated with a secondary bacterial pneumonia are more severe.[6] Since Covid-19 is an infectious disease that gravely endanger the lives of critically ill patients, thereby it is extremely vital to determine the clinical implication of secondary pulmonary bacterial infection in critically ill ones with severe Covid-19, for the sake of prognostic assessment and therapeutic guidance. 19 is an emerging and evolving infectious and communicable diseases which gravely endanger the lives of critically ill patients with it. It is crucial to determine the clinical implication of secondary pulmonary bacterial infection for the outcome of critically ill patients with severe Covid-19

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