Abstract
目的 探讨多发性骨髓瘤(MM)的核素全身骨显像和X线影像特征,评估核素骨显像在MM骨病诊断中的临床应用价值.方法对49例多发性骨髓瘤患者53例次99mTc-MDP核素骨显像与X线摄片结果进行对比研究.结果①核素全身骨显像阳性率为84.8%(151/178个),共发现病灶151个.X线摄片阳性率为56.7%(101/178个),共发现病灶101个.两种显像的诊断符合率为41.6%(74/178个).②对受检病例骨损害的好发部位及频率的统计表明:核素显像依次为脊柱(37.1%)、肋骨(25.2%)、骨盆(10.6%)、长管状骨6.6%、肩关节及肩胛骨(6.6%)、颅骨(3.3%);X线摄片结果为脊柱(36.6%)、肋骨(15.8%)、颅骨(14.9%)、骨盆(14.9%)、长管状骨(8.9%)、肩关节及肩胛骨(4.0%).核素显像对肋骨病灶的显示较X线更敏感,而颅骨病变则更适于行X线检查.核素骨显像对X线阳性的不同影像特征病灶的检出率亦不同(P<0.01),分别为病理性骨折100%、溶骨性破坏68.4%、弥漫性骨质疏松62.5%.③X线摄片和核素骨显像相结合与单独X线摄片(部分加做局部CT或MRI)探测骨损害对受检病例MM分期结果有一定影响.结论核素骨显像与常规X线摄片检查对多发性骨髓瘤的骨损害探测各有所长,二者相互补充,核素骨显像可以作为探测多发性骨髓瘤骨损害的常规方法。
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