The clinical effectiveness of different concentrations of procaine for mandibular extractions

Abstract

1. 1. The results of 865 inferior alveolar nerve injections with different concentrations of procaine (using epinephrine, 1:50,000, or Neosynephrine, 1:2,500, as vasoconstrictor) for mandibular extractions, were analyzed. 2. 2. Using epinephrine, 1:50,000, as vasoconstrictor, it was found that 1.5 per cent procaine was as effective as 2 per cent or 4 per cent for mandibular extractions. One per cent procaine was less effective than the higher concentrations. 3. 3. Using Neosynephrine, 1:2,500, as vasoconstrictor, it was found that 2 per cent procaine was as effective as 4 per cent procaine for mandibular extractions. One per cent and 1.5 per cent procaine were less effective than 2 per cent or 4 per cent procaine. 4. 4. One and one-half per cent procaine with epinephrine, 1:50,000, may be more effective for mandibular extractions than 1.5 per cent procaine with Neosynephrine, 1:2,500. 5. 5. The theoretical possibility of poorer technique on the part of students compared with that of instructors could not have influenced the results obtained in this study.