The clinical cariostatic effectiveness of two concentrations of acidulated phosphate-fluoride mouthwash

Abstract

Two acidulated phosphate-fluoride mouthwashes that contained either 100 or 200 ppm of fluoride ion were compared with a placebo mouthwash to determine their anticariogenic effectiveness. The twice-daily use of an acidulated phosphate-fluoride mouthwash that contains a small amount of fluoride is effective in reducing the incidence of dental caries in children. Two acidulated phosphate-fluoride mouthwashes that contained low concentrations of fluoride were compared to determine their effectiveness in reducing dental caries in children. Children were randomly assigned to one of three groups in which they received mouthwashes containing either 100 or 200 ppm of fluoride ion or a placebo mouthwash. After 26 months, statistically significant differences in caries increments were found between both test groups and the control group. No significant statistical differences were found between the two acidulated phosphate-fluoride formulations, but both were shown to be effective in reducing caries.