The Clinical and Spirometric Profiles and Staging of COPD, Asthma in Smokers and Nonsmokers, Bangladesh

Abstract

Objective: In this study our main goal is to evaluate the clinical and spirometric profiles and staging of COPD, asthma in smokers and nonsmokers, Bangladesh. Method: This cross-sectional study was carried out at Tertiary medical College Hospital, Bangladesh. Where data were collected from July 2019 to June 2020. A total of 332 where 232 smoker having exposure to >10 pack year smoking fulfilling inclusion and exclusion criteria were included and 100 apparently healthy non-smoker also were included as control. Results: During the study, among smokers, clinically 11 and 5 were diagnosed to have COPD and asthma only and the spirometry also diagnosed these 9 smokers and other 31 smokers more to have COPD and thus diagnose 42 smokers to have COPD. Also, 9 smokers to have asthma. The difference between clinical and spirometrically diagnosis of COPD and asthma were statistically highly significant, 0.001. whereas, among non-smokers. Where among 100 nonsmokers only 2 have COPD and asthma. The value of FEV1 of smokers and non-smokers people were 3.1302 and 3.2450 respectively and their standard deviation were 0.52207 and 0.44162 respectively. This difference in FEV1 value was statistically significant (p value 0. 006. The value of FVC of smokers and non-smokers were 4.0857 and 4.2096 respectively and standard deviations were 1.47849 and 0.50218 respectively. Also, 56% and 50% had mild level of COPD and asthma severity. Conclusion: For long-term primary care smokers, these findings have major consequences. The advantages may include further reason for spirometry which might open the door to improved targeting due to variations in the appropriate therapy.