The Clinical and Laboratory Profile of RT-PCR Positive Covid-19 Patients in District Hospital in Bangladesh

Abstract

Objective: To assess the clinical and laboratory profile of RT-PCR positive covid-19 patients in district hospital in Bangladesh. Method: This cross-sectional study was done in 250 Bed General Hospital, Tangail, Bangladesh from January 2021 to Dec 2021. We included 95 patients having clinical symptoms and signs of COVID-19, above the age of 18 years, irrespective of sex. We defined probable and confirmed COVID-19 case according to ‘National Guidelines on Clinical Management of Corona Virus Disease 2019 (COVID-19) Version 7.0, published on 28 May 2020.10 Data were collected in structured questionnaire from patients and hospital records. All laboratory tests were performed according to the clinical judgement. Laboratory assessments consisted of RTPCR for COVID-19, complete blood count, coagulation tests, assessment of liver and renal function, C-reactive protein, procalcitonin, lactate dehydrogenase (LDH) and ferreting. Radiological assessments included chest x-ray and high resolution computed tomography (HRCT) scan. Results: During the study, majority were belong to >56 years age group, 43.6% were female and 56.4% were male. Plus, majority didn’t get their vaccination, 89.60%. In addition to that, 42.1% had DM followed by HTN cases was 36.8%, 8.4% had previously history of stroke, 10.5% had CKD. 69.5% had anorexia followed by 58.9% had nausea, 28.4% had vomiting, 14.7% had Abdominal pain. On laboratory investigations, we found most of the patients had elevated levels of C-reactive protein and D-dimer was positive in 99% cases. Plus,75% patient presents emergency signs with SpO2 <90% or respiratory rate >24. Conclusion: Considering the data of this investigation, it can be stated that, COVID-19 impacted mostly senior male patients. Most of them were diabetic and hypertensive. Common symptoms anorexia sore throat, diarrhea, vomiting, nausea, stomach ache. Key test results included lymphopenia, elevated CRP, positive D-dimer. Notwithstanding that most didn’t take ......