The clinical analysis of radioclide imaging and patent blue V in prevention of lymphorrhea after operations in fold inguen＇s space prospective randomized trial

Abstract

Objective To evaluate the clinical effect of radioclide imaging and Patent Blue V on lymphorrhea after operations in fold inguen＇ s space. To use radioclide imaging and Patent Blue V to prevent or cure lymphorrhea, so we can lower the incidence of lymphorrhea at the most. Methods Fourty patients undergoing operated in fold inguen＇ s space were randomized into tWO group ： control group （ n = 20） without using radioclide imaging and Patent Blue V and treatment group （n =20） with this technology applied to the dissection area at the begin of the surgical procedure. For each group, the mean daily postoperative drainage volume, the mean cumulative drainage quantity 4 days after operation and the incidence of lymphorrhea were reported. The analysis was used to evaluate the medical effect of using radioclide imaging and Patent Blue V in surgery in fold inguen＇ s space. It was logical to hope that application of Radioclide imaging and Patent Blue V after operations in fold inguen＇ s space would reduce lymphorrhea. Results The mean daily postoperative drainage was significantly greater in control group （P 〈 0. 05 ）. The mean cumulative drainage quantity 4 days after the operation was （ 125. 1 ± 23.7 ） ml and （ 369. 9 ± 31.7 ） ml in treatment group and control group respectively, the reduction of cumulative drainage was 59. 6% （P 〈 0. 05）. The incidence of lyrnphorrhea was 0% （0 cases） and 10% （2 cases） in treatment group and control group respectively. （P 〈 0. 05）. One wound complications （50%） occurred in patients with postoper- ative lymphorrhea, and 0 （0%） occurred in those without postoperative lymphorrhea （P 〈 0. 01 ）. The total drainage duration and mean postoperative hospital stay was （ 10. 2 ± 2. 5） and （ 19. 5± 4. 5） days in lymphorrhea group, there were （ 3.5 ± 0. 8 ） and （7. 6± 1.2） days in goupe without lymphorrhea （ P 〈 0. 05）. Conclusion Radioclide imaging and Patent Blue V can reduce the daily and total cumulative postoperative drainage volume, and decrease the incidence of postoperative lymphorrhea after operation in fold inguen＇ s space. Key words: Radioclide imaging; Patent blue V ; Following; Prevention; Lymphorrhea