The CKD-EPI Equation and MDRD Study Equation Find Similar Prevalence of Chronic Kidney Disease in Asian Populations

Abstract

Letters15 December 2009The CKD-EPI Equation and MDRD Study Equation Find Similar Prevalence of Chronic Kidney Disease in Asian PopulationsAndrew S. Levey, MD, Lesley A. Stevens, MD, MS, and Josef Coresh, MD, PhDAndrew S. Levey, MDFrom Tufts Medical Center, Boston, MA 02111; and Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.Search for more papers by this author, Lesley A. Stevens, MD, MSFrom Tufts Medical Center, Boston, MA 02111; and Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.Search for more papers by this author, and Josef Coresh, MD, PhDFrom Tufts Medical Center, Boston, MA 02111; and Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-151-12-200912150-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Sabanayagam and colleagues report that mean estimated GFR when computed with the CKD-EPI equation is higher than with the MDRD Study equation in a young Asian sample (presumably with high GFR) of mixed ethnicity. This confirms our findings in a predominantly U.S. and European sample and is expected because of the form and coefficients for the variables for both equations. Studies with measured GFR must evaluate the accuracy of GFR estimates in Asian persons. The CKD-EPI equation has no “Asian coefficient,” so we suspect that it will not be as accurate in Asian persons as in our ...