Abstract
✓ Experimental hydrocephalus was created in dogs by injection of kaolin into the cisterna magna. One month after the kaolin injection, ventriculojugular shunts were performed on certain of the hydrocephalic dogs. Shunted hydrocephalic dogs were killed 1 day or 1 week after placement of the shunt. Cerebrospinal fluid (CSF) pressures were measured prior to the kaolin administration and/or 1 month post-kaolin injection and/or after the shunting procedure. Choroid plexuses from control, hydrocephalic, and shunted hydrocephalic dogs were examined by light and electron microscopy. The hydrocephalic dogs had choroid plexuses with a flattened epithelium, compacted cytoplasm, and multiple large vacuoles usually containing small, rounded membrane-bound structures; it was postulated that these vacuolar structures were dilated multivesicular bodies possibly related to CSF resorption. Choroid plexuses from hydrocephalic dogs examined 1 day post-shunt closely resembled choroid plexuses from the control dogs. Intracytoplasmic, apical lipoid inclusions, 1.0 to 6.0 µ in diameter, were noted within many choroidal epithelial cells of dogs shunted for 1 week. This change was probably related to the trauma of shunt insertion. It was concluded that the morphology of the canine choroid plexus returned to normal 1 day after the ventriculojugular shunt.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.