Abstract
The 1 : 2 chlorhexidine : β-cyclodextrin(Cx : βCD) complex was prepared and characterised using X-ray crystallography, infrared spectroscopy, thermal analysis and nuclearmagnetic resonance. The minimum inhibitory concentration (MIC50) of the chlorhexidine : β-cyclodextrin inclusion compoundagainst Streptococcus mutans, Eubacterium Lentum, Fusobacterium nucleatum, Bacteroides fragilis andActinomices actinomycetemcomitans was determined. TheCx : βCD inclusion compound inhibited the bacterial growth at a low concentration.
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