Abstract
ObjectiveAimed to summarize the characteristics of chest CT imaging in Chinese hospitalized patients with Coronavirus Disease 2019 (COVID-19) to provide reliable evidence for further guiding clinical routine.MethodsPubMed, Embase and Web of Science databases were searched to identify relevant articles involving the features of chest CT imaging in Chinese patients with COVID-19. All data were analyzed utilizing R i386 4.0.0 software. Random-effects models were employed to calculate pooled mean differences.Results19 retrospective studies (1332 cases) were included. The results demonstrated that the combined proportion of ground-glass opacities (GGO) was 0.79 (95% CI 0.68, 0.89), consolidation was 0.34 (95% CI 0.23, 0.47); mixed GGO and consolidation was 0.46 (95% CI 0.37; 0.56); air bronchogram sign was 0.41 (95% CI 0.26; 0.55); crazy paving pattern was 0.32 (95% CI 0.17, 0.47); interlobular septal thickening was 0.55 (95% CI 0.42, 0.67); reticulation was 0.30 (95% CI 0.12, 0.48); bronchial wall thickening was 0.24 (95% CI 0.11, 0.40); vascular enlargement was 0.74 (95% CI 0.64, 0.86); subpleural linear opacity was 0.28 (95% CI 0.12, 0.48); intrathoracic lymph node enlargement was 0.03 (95% CI 0.00, 0.07); pleural effusions was 0.03 (95% CI 0.02, 0.06). The distribution in lung: the combined proportion of central was 0.05 (95% CI 0.01, 0.11); peripheral was 0.74 (95% CI 0.62, 0.84); peripheral involving central was 0.38 (95% CI 0.19, 0.75); diffuse was 0.19 (95% CI 0.06, 0.32); unifocal involvement was 0.09 (95% CI 0.05, 0.14); multifocal involvement was 0.57 (95% CI 0.48, 0.68); unilateral was 0.16 (95% CI 0.10, 0.23); bilateral was 0.83 (95% CI 0.78, 0.89); The combined proportion of lobes involved (> 2) was 0.70 (95% CI 0.61, 0.78); lobes involved (≦ 2) was 0.35 (95% CI 0.26, 0.44).ConclusionGGO, vascular enlargement, interlobular septal thickening more frequently occurred in patients with COVID-19, which distribution features were peripheral, bilateral, involved lobes > 2. Therefore, based on chest CT features of COVID-19 mentioned, it might be a promising means for identifying COVID-19.
Highlights
The Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, a new coronavirus of the Sarbe virus subgenus, a member of the orthocoronavirus subfamily [1]. †Haitao Yang and Yuzhu Lan have contributed to this workDepartment of Pulmonary and Critical Care Medicine, Shengli ClinicalMedical College of Fujian Medical University, Fujian Provincial Hospital, Dongjie Road No 134, Fuzhou 350001, Fujian, ChinaThe outbreak of the COVID-19 has resulted in a global pandemic
The results demonstrated that the combined proportion of ground-glass opacities (GGO) was 0.79, consolidation was 0.34; mixed
Based on chest computer tomography (CT) features of COVID-19 mentioned, it might be a promising means for identifying COVID-19
Summary
The Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, a new coronavirus of the Sarbe virus subgenus, a member of the orthocoronavirus subfamily [1]. The outbreak of the COVID-19 has resulted in a global pandemic. (early detection, early diagnosis, early isolation and early treatment) are important. The varieties of clinical manifestations, laboratory tests and imaging tests limit clinical diagnosis and treatment. Imaging can be used to guide diagnosis early in the course of the disease or in asymptomatic patients. Chest CT played an important role in timely detecting lung abnormalities, allowing for early treatment. It is urgent to conduct this meta-analysis to comprehensively summarize the characteristics of CT imaging of patients with COVID-19 to further guide clinical and scientific research through evidence-based medicine
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