Abstract

Chloromethylation of p-nitrophenol or its alkyl ethers gave reactive 2-chloromethyl intermediates which have been converted into 2-hydroxymethyl-(VII), 2-mercaptomethyl-(II), or 2-aminomethyl-4-nitrophenyl ethers (X), and various acyl, alkyl, aryl, and sulphone derivatives. The amines (VIII) obtained on reduction have been studied as schistosomicides.

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