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Abstract
A number of mild methods for the preparation of 2-substituted 5-normonyloxazoles (1) by dehydrative cyclisation of the corresponding monamides (2) have been developed and are described. The preferred conditions involve using trichloroacetyl chloride, pyridine, and 4-N,N-dimethylaminopyridine. The stabilities of the vinyloxazoles to both the reaction conditions and to light are also reported.
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