Abstract

The present study was designed to shed light on a topic rarely explored and to suggest possible ways to detect risk factors for the presence of suicidal ideation and behaviors in a sample of adult patients with Attention-Deficit Hyperactivity Disorder (ADHD). This study also explored the association between ADHD, affective temperaments, the presence of hypomania symptoms, and suicide risk. We hypothesized that (compared to healthy controls) (1) patients with adult ADHD would report more negative affective temperaments and more hypomania symptoms and (2) that they would have a higher suicide risk. The participants included 63 consecutive adult inpatients (18 women, 45 men) with ADHD and 69 healthy controls (42 women, 22 men). All participants were administered the Wender Utah Rating Scale (WURS), the Hypomania Check-List-32 (HCL-32), the Mood Disorder Questionnaire (MDQ), the Temperament Evaluation for Memphis, Pisa, Paris, and San Diego (TEMPS-A), and the Columbia-Suicide Severity Rating Scale (C-SSRS). Forty-six percent of the ADHD patients had an Axis 1 comorbid disorder. ADHD patients (compared to controls) more often reported suicidal ideation (46.0% vs. 5.9%, one-way Fisher exact test p < 0.001; phi = 0.46). ADHD patients and the controls also significantly differed in all the scales administered (with Cohen’s d between 0.92–4.70), except for the TEMPS-A Hyperthymia scale. A regression model indicated that ADHD was independently associated with higher scores of a negative temperaments/hypomania factor (Odd Ratio = 14.60) but not with suicidal ideation. A high incidence of suicidal ideation, comorbid psychiatric disorders, and negative affective temperaments was reported in adult ADHD patients, and clinicians should routinely assess risk factors for suicide among these patients.

Highlights

  • Attention-Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with childhood-onset, marked by high and consistent levels of inattention, impulsivity, and/or hyperactivity that must be diagnosed before the age of 12 and can lead to functional impairment in multiple domains [1]

  • The aim of the present study is to investigate the presence of suicidal ideation and behaviors in a sample of adult patients with ADHD and to explore the association between ADHD, affective temperaments, the presence of hypomania symptoms, and suicide risk

  • The ADHD patients and controls differed in sex and age but only before correction for multiple testing (t130 = −2.97, p = 0.004)

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Summary

Introduction

Attention-Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with childhood-onset, marked by high and consistent levels of inattention, impulsivity, and/or hyperactivity that must be diagnosed before the age of 12 and can lead to functional impairment in multiple domains (familial, social, academic, and work-life) [1]. The predominance of symptoms varies between individuals and over time in the same individual, giving rise to different configurations of the disease: Int. J. Res. Public Health 2020, 17, 2871; doi:10.3390/ijerph17082871 www.mdpi.com/journal/ijerph

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