The characteristics observation of the contrast-enhanced ultrasound about the lesions of the late and recurrent small hepatic cellular cancer

Abstract

Objective To analyze the imaging characteristics and clinical value of contrast-enhanced ultrasound (CEUS) in recurrent small hepatocellular carcinoma (RsHCC). Methods A series of 52 patients with 68 lesions of the primary small hapatocellular carcinoma were included as the control group. Two hundred and ninety-three patients who were the first recrudescing cases during 2 years, with 367 lesions were treated as group R1. Meanwhile, 46 patients with 51 lesions of the first recrudescing in 2 years later were included as group R2. The hemodynamic parameters in the forms of enhanced beginning time, time to peak intensity, time to fade, time to hypoenhancing of these three groups were analyzed and compared. Results Compared with control group and group R1, the basic time, peak time, and the time when physical sign of fade away and the low echo time begins in group R2 were significantly increased(P 0.05). Compared with control group and group R1 respectively, group R2 presented some statistical differences in the arterial phase and delayed phase (P 0.05). The distribution of the ultrasonic imaging in each phase of group R1 and control group had no significant difference (P>0.05). Conclusions The perfusion pattern of late-onset RsHCC CEUS is still priority to fast forward retreat quickly, but also presents the diversification trend. Studied the enhancement patterns of RsHCC combined with the other related information maybe provides a convenient and valuable method for the clinic. Key words: Contrast-enhanced ultrasound; Recurrent small hepatocellular carcinoma; Perfusion pattern