Abstract

The article presents results of comparative evaluation of age-sex, social and clinical structure of patients with tuberculosis of lungs, primarily detected in Zheleznogorsk in 1993-2000 and 2008-2013. The average indicator of tuberculosis morbidity in these two periods amounted to 29.8 per 100 000 of population and indicator of mortality amounted to 1.8 and 4.7 per 100 000 of population correspondingly. It is established that despite significantly lower epidemiological indicators as compared with average national indicators, the manifestations of negative pathomorphosis were revealed: deterioration of structure of clinical forms and characteristics of specific process; manifestation of cases of tuberculosis combined with HIV-infection; increasing of epidemiological danger for ill patients against the background of deterioration of their social structure at the expense of persons having no family, no job, residing in unfavorable housing conditions, homeless, and persons with harmful habits and drug addicted. It is proposed to take into account established aggravating factors while organizing check-up fluorography of population for tuberculosis. The conclusion is made about necessity of increasing of quality of activities concerning active detection of tuberculosis in population, especially the categories whose significance increased in formation of indicator of morbidity. Also, it is necessary to implement effective preventive activities with persons in contact with patients with tuberculosis.

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