Abstract

Septicemia is one of the important causes of morbidity and mortality. Emergence of multidrug resistant bacteria is a major problem in the management of septicemia. Present study was undertaken to isolate the common bacterial pathogens associated with septicemia and determine their antibiotic resistance. Blood cultures from 100 suspected cases of septicemia were examined. The growths from the subcultures were identified by conventional biochemical tests. Antibiotic susceptibility testing done by Kirby-Bauer disk diffusion method and antibiotic resistant strains in the primary screening were further processed for MRSA, ESBL and MBL production. Out of 100 suspected cases, 28 (28%) were cultures positive. Of which 15 (53.57%) were Gram positive cocci and 13 (46.42%) were Gram negative bacilli. The prevalence of MR CONS was found to be high 78% when compared to MRSA 67%. The overall prevalence of ESBL producers among Gram negative bacilli was found to be 46% and MBL among Pseudomonas aeruginosa was 33%.Thus, the study highlights the rising level of antibiotic resistance amongst the bacterial isolates from blood and, hence, the need to continuously monitor the locally emerging antibiotic resistance patterns, and updates the existing antibiotic policies.

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